CAV 2017 is the 29th in a series dedicated to the advancement of the theory and practice of computer-aided formal analysis methods for hardware and software systems.  The conference covers the spectrum from theoretical results to concrete applications, with an emphasis on practical verification tools and the algorithms and techniques that are needed for their implementation. CAV considers it vital to continue spurring advances in hardware and software verification while expanding to new domains such as biological systems and computer security. The proceedings of the conference will be published in the Springer-Verlag Lecture Notes in Computer Science series. A selection of papers is expected to be invited to a special issue of Formal Methods in System Design and the Journal of the ACM.